Biology of PRP


Ann Burns Fire Disasters. 2012 December 31; 25(4): 207–213. Published online 2012 December 31.

PMCID: PMC3664531Development of a cost-effective method for platelet-rich plasma (PRP) preparation for topical wound healing K. AkhundovG. Pietramaggioril. WaselleS. DarwicheS. GueridC. ScalettaN. Hirt-BurriL.A. Applegate,° and W.V. Raffoul°

Platelet-Rich Plasma: A Milieu of Bioactive Factors

Stacie G. Boswell, D.V.M., Brian J. Cole, M.D., M.B.A., Emily A. Sundman, B.S., Vasili Karas, B.S., and Lisa A. Fortier, D.V.M., Ph.D.

Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol 28, No 3 (March), 2012: pp 429-439

29. Bendinelli P, Matteucci E, Dogliotti G, et al. Molecular basis of anti-inflammatory action of platelet-rich plasma on human chondrocytes: Mechanisms of NF-KB inhibition via HGF. J Cell Physiol 2010;225:757-766. Modulation of coagulation and vascular repair by GFs in PRP is theorized to result in accelerated and improved wound, tendon, ligament, and bony healing.

12. Sanchez M, Anitua B, Azofra J, Andia I, Padilla S, Mujika I. Comparison of surgically repaired Achilles tendon tears using platelet-rich fibrin matrices. Am J Spans Med 2007;35:245-251.

McCarrel and Fortier14 14. McCarrel T, Fortier L. Temporal growth factor release from platelet-rich plasma, trehalose lyophilized platelets, and bone marrow aspirate and their effect on tendon and ligament gene expression. / Orthop Res 2009;27:1033-1042.

Platelet-Rich Plasma: Quantitative Assessment of Growth Factor Levels and Comparative Analysis of Activated and Inactivated Groups

Jeong Woo Lee1, O Hyun Kwon1, Taek Kyun Kim1, Young Kyoo Cho1,Kang Young Choi1, Ho Yun Chung1, Byung Chae Cho1, Jung Dug Yang1, Jun Ho Shin2

1Department of Plastic and Reconstructive Surgery, Kyungpook National University School of Medicine, Daegu; 2Shin Jun Ho Plastic SurgeryClinic, Seongnam, Korea

PRP Matrix Grafts

Current Knowledge and Application Techniques in Musculoskeletal Medicine

David M. Crane, MD;  Peter A.M. Everts, PhD