Fertility PRP Applications with Alocuro PRO-PRP
Supporting Endometrial and Ovarian Health with Regenerative PRP
Platelet-Rich Plasma (PRP) is an emerging regenerative therapy within reproductive medicine, used to optimise tissue health and receptivity in women experiencing complex fertility challenges. By delivering autologous growth factors and cytokines directly into reproductive tissue, PRP provides a biologically active and minimally invasive option that complements existing assisted reproduction strategies.
Alocuro’s PRO-PRP system enables clinicians to prepare high-concentration, sterile PRP at the point of care, ensuring consistency, purity, and optimal regenerative potential in every treatment.
Mechanism of Action: Biological Support for Reproductive Tissues
Platelets contain a dense concentration of growth factors that initiate and regulate tissue repair. When activated, they release signalling molecules that can:
Stimulate angiogenesis and cellular proliferation
Improve endometrial thickness and receptivity
Enhance local blood flow and microvascular function
Support regeneration in the ovarian cortex and follicular microenvironment
These mechanisms underpin PRP’s use across two key fertility pathways: intra-uterine PRP and intra-ovarian PRP.
Clinical Applications
Intra-Uterine PRP (IUI-PRP)
IUI-PRP involves the infusion of a small PRP volume into the uterine cavity. It is performed as an outpatient procedure and has an excellent safety profile due to the autologous nature of the injectate.
Clinical research demonstrates that intra-uterine PRP can benefit patients with:
Thin or refractory endometrium (<6 mm)
Repeated implantation failure
Post-surgical Asherman’s syndrome or chronic endometritis
PRP infusion has been shown to increase endometrial thickness, improve receptivity, and enhance clinical pregnancy and live birth rates.
Australian clinicians using Alocuro PRP have reported significant improvements in frozen embryo transfer rates and endometrial thickness in patients previously unresponsive to conventional therapy.
Training and Clinical Support
Alocuro provides comprehensive clinician education and procedural resources for fertility PRP, covering:
Intra-uterine and intra-ovarian protocols
Device operation and preparation techniques
Patient selection and counselling frameworks
Evidence summaries and regulatory guidance
Access to these modules and support materials is reserved for verified clinicians through the Alocuro Clinician Portal.
Why Alocuro PRO-PRP for Fertility Practice
High platelet recovery and concentration (up to 9× baseline) – ensuring strong biological activity in low-volume procedures
Closed, sterile, gel-free system – no chemical activators or thixotropic gels, maintaining platelet viability and patient safety
Customisable plasma yield – enabling the precise small-volume preparation required for IUI and IO fertility protocols
Proven Australian clinical use – incorporated in reproductive clinics and research audits since 2021
Intra-Ovarian PRP (IO-PRP)
Intra-ovarian PRP involves injecting a high-concentration PRP directly into the ovarian cortex under ultrasound or laparoscopic guidance. The approach aims to rejuvenate aging or low-functioning ovarian tissue and enhance follicular activity in women with diminished ovarian reserve (DOR), premature ovarian insufficiency (POI), or poor response to IVF stimulation.
Evidence from observational studies and clinical audits has demonstrated:
Significant increases in AMH levels and antral follicle count
Reduction in FSH levels
Improved oocyte and embryo yield in subsequent IVF cycles
Australian studies using Alocuro PRP systems have documented measurable ovarian response improvements in women aged 35–45 years with long-standing subfertility.
Interested in the Research?
Alocuro maintains a curated library of peer-reviewed articles and clinical studies supporting the use of PRP in reproductive medicine. If you would like access to our collection of scientific literature, including independent trials and outcome data aligned with our system, please contact our team directly.
Reach out via info@alocuro.com.au to request access to our collated research summaries and literature library.