Advanced Platelet-Rich Fibrin (PRF) Protocol for Aesthetic Regeneration
One System. Two Regenerative Solutions.
Alocuro’s advanced platelet-concentrating system empowers clinicians to perform both Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF) treatments using the same closed, TGA-listed device. This delivers exceptional clinical flexibility and eliminates the need for additional equipment.
Whether you’re targeting high-dose platelet therapy with PRP or natural fibrin-based regeneration with Pure PRF+, Alocuro’s system allows you to tailor treatments to each patient, efficiently, safely, and with confidence.
Overview: What is Pure PRF+?
Pure PRF+ is Alocuro’s advanced platelet-rich fibrin (PRF) protocol — a 100% autologous treatment that uses the patient’s own blood to deliver a fibrin matrix enriched with platelets, stem cells, growth factors, and exosomes for regenerative tissue support.
Unlike PRP, Pure PRF+ contains no anticoagulants or additives. It mimics the body’s natural healing process by forming a soft fibrin scaffold within 30 minutes of preparation, making it ideal for dermal and subdermal rejuvenation.
How It Works
The PRF preparation process collects and concentrates the patient’s platelets and stem cells above the red blood cell layer, forming a yellow, RBC-depleted plasma. Within 30 minutes, this plasma forms a fibrin scaffold that binds and slowly releases regenerative proteins.
Key mechanisms:
Natural platelet activation at the time of blood collection
Slow-release matrix for prolonged cytokine and growth factor delivery
Temporary dermal scaffold supporting tissue structure and repair
Why Add Pure PRF+ to Your Practice?
100% natural – no anticoagulants, additives, or foreign substances
Subtle structural support – delivers short-term volume and regenerative instruction
Reduced downtime – minimal bruising and swelling due to blunt cannula delivery
Ideal for sensitive areas – tear troughs, hands, neck, décolletage, and scalp
Microneedling compatible – PRF serum can be applied topically and needled into skin
Perfect for PRP hyper-responders – lower platelet per mL, less sting or swelling
How Pure PRF+ is used
Pure PRF+ can be injected via blunt-tip cannula or microneedled topically. Common treatment areas with evidence-based clinical indications include:
Tear trough (volume & dark circles)
Pan-facial rejuvenation (to improve facial fat pads and muscle health)
Neck & décolletage
Back of hands
Scalp (hair rejuvenation)
Handling Notes for Clinicians
Short working time: Must be injected within 30 mins of blood draw
Cannula-only: Viscosity requires 22G blunt-tip cannula
All plasma must be collected: To maximise growth factor delivery
Variable patient haematocrit affects total plasma volume and viscosity
No local anaesthetic required: Minimises patient discomfort and recovery time